A trial conducted by North Carolina State University* demonstrated the effectiveness of fluralaner, an isoxazoline insecticide against bed bugs (Cimex lectularius).  This hematophagous ectoparasite has recently reappeared in barn-housed hens.  The product is available commercially as Exzolt® to be administered at a dose rate of 0.5 mg/kg body weight.  It was determined that the product was effective against pyrethroid and fipronil-resistant bed bugs. These parasites feeding on chickens within 28 days of treatment were killed. 

Exzolt® is also used to treat red mite (Dermanyssus gallinae) infestation with a manufacturer’s recommendation of two doses in drinking water at seven-day intervals. Exzolt® can be administered to laying flocks without the need to withhold eggs from market.

*Gonzalez-Morales, M. et al. Systemic veterinary drugs for control of the common bed bug, Cimex lectularius, in poultry farms. Parasites & Vectors. DOI:10.1186/s13071-022-05555-6 (2022)