Dr. Frances S. Collins, Director of the National Institutes of Health (NIH) has announced an initiative partnering his institute with industry leaders to accelerate progress in combating COVID-19 and future pandemics. The Accelerating COVID-19 Therapeutic Interventions and Vaccines Initiative (ACTIV) has been established by the NIH and the Foundation for the NIH. A total of eighteen biopharmaceutical companies, federal agencies and the EU Medicine Agency are involved.
The initiative was outlined in a viewpoint article* published in the journal of The American Medical Association.
ACTIV comprises four working groups co-shared by a scientist from NIH and a colleague from industry.
The working groups will comprise:-
- Therapeutics Clinical Working Group to determine the benefits of drug therapy for COVID-19
- Preclinical Working Group to evaluate testing of candidate therapy and vaccines
- Clinical Trial Working Group to establish efficient test systems for therapy and vaccines
- The Vaccines Working Group, focusing on evaluation of vaccine candidates

*Collins, F. S., and Stoffels, P. Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): an unprecedented partnership for unprecedented times. JAMA. DOI:10.1001/jama.2020.8929 (2020)