Hy-Line International has prepared a Technical Bulletin to guide producers to prevent Genotype VII viscerotropic velogenic Newcastle disease with a specific emphasis on vaccination. This condition has caused extensive losses over the past decade in Asia, the Middle East and Latin America. The Bulletin describes the clinical signs, gross and microscopic lesions with illustrations. Intervention strategies including vaccination and recommendations for application are detailed. The range of vaccines available ranging from mild to highly antigenic are tabulated together with suggestions on frequency of administration to stimulate solid immunity against this form of Newcastle disease.